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September 10, 2025JDDG Journal der Deutschen Dermatologischen GesellschaftOpen Access

Leukemia cutis with concomitant acrodermatitis chronica atrophicans and chronic B‐cell lymphocytic leukemia: complete clearance under doxycycline therapy

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Authors

SBSven‐Niklas BurmannTGThilo GambichlerJBJürgen C. Becker

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Overview

Case report reveals complete resolution of leukemia cutis and acrodermatitis chronica atrophicans, suggesting doxycycline's potential role in lymphoma therapy.

Key Points

  • Complete clearance of leukemia cutis was achieved after doxycycline treatment in a patient with CLL.
  • The patient had a chronic Borrelia burgdorferi infection, confirmed by PCR analysis and serology.
  • Clinical resolution of skin lesions occurred without initiation of CLL-specific therapy during follow-up.
  • Doxycycline may represent a novel therapeutic approach for managing skin manifestations related to CLL.

Cite This Study

Burmann et al. (2025) studied this question.

synapsesocial.com/papers/68c1dda254b1d3bfb60fc75ehttps://doi.org/10.1111/ddg.15868
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