Case report highlights malignant transformation risk in discoid lupus erythematosus, suggesting need for careful monitoring.
Discoid lupus erythematosus (DLE) is a benign disorder of the skin, clinically characterized by red scaly patches which heal with atrophy, scarring and pigmentary changes. DLE is subdivided into a localized form in which lesions are confined to the face and neck or a disseminated form in which lesions also occur elsewhere on the body. Malignant transformation is a rare complication of this condition. We report a case of squamous cell carcinoma (SCC) developing over lesions of disseminated DLE. A 60 years male diagnosed as a case of Discoid lupus erythematosus (DLE) developed Squamous cell carcinoma from the lesions over a period of 5 years due to treatment gap and late follow up. Diagnosis was based on physical and histopathological examination, the absence of systemic involvement and routine laboratory parameters, which were all within normal range. It is every essential to counsel the diagnosed cases of DLE and warn all patients about all the possible outcomes and compliance with medications should be ensured
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Gupta et al. (2023) studied this question.
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