Novel Advances and Recent Updates in The Crosstalk Between Neuroplasticity and Addiction

Undisputedly, the brain is the most complex organ in the human body, especially due to the paucity of understanding of its normal functioning and pathophysiology. However, the brain is characterized by its unique ability, called neuroplasticity, which facilitates the addiction and deaddiction of various habits or substances. The term ‘neuroplasticity’ is often used to describe the brain's ability to precipitate structural and functional changes, in response to particular experiences. While the neuroplastic nature of the brain helps in learning new languages and mastering demanding sports, it can also result in addictive disorders from substance abuse or detrimental habits. With recent advancements in the understanding and subsequent development of treatment modalities, there has been significant progress in rehabilitation and management of problems stemming from addiction. This article aims to review the various novel advancements devised for modifying neuroplasticity, to combat addiction to substance abuse.