Review article discusses digital biomarkers and AI-enhanced neuropsychological tests for dementia screening.
Dementia is becoming a serious social and healthcare issue worldwide. While recent studies suggest that timely intervention can prevent its progression, most patients with dementia remain undiagnosed. The low diagnosis rate is mainly caused by the lack of an efficient screening tool for dementia. The first step toward diagnosing dementia involves cognitive assessments with interview-based neuropsychological tests, which have a well-established clinical utility. Traditional neuropsychological tests have high validity and reliability for dementia testing; however, they have limitations such as high test-related burdens and inter-rater variability of the results. Digital technologies with artificial intelligence have transformed traditional cognitive tests into efficient tools for dementia screening. This review article introduces recent developments in the research on digital biomarkers for dementia and discusses their limitations in clinical settings.
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Shuko Takeda (2025) studied this question.
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