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September 14, 2025

Association between the cholesterol, high-density lipoprotein, and glucose index and type 2 diabetes mellitus prevalence in US adults: A cross-sectional study based on National Health and Nutrition Examination Survey 2009-2018.

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Cross-sectional analysis reveals CHG index significantly associates with type 2 diabetes prevalence, indicating potential utility as a biomarker.

A higher CHG index is associated with increased type 2 diabetes prevalence, indicating its potential significance.
Participants with a CHG index greater than 5.24 experienced increased odds of type 2 diabetes, supporting the index's predictive value.
The study used weighted logistic regression to assess associations between the CHG index and diabetes prevalence among a large sample.
Findings suggest the CHG index could be a useful, accessible biomarker for identifying diabetes risk early, warranting further research.

Zhang et al. (2025) studied this question.

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Cross-sectional analysis reveals CHG index significantly associates with type 2 diabetes prevalence, indicating potential utility as a biomarker.