Genome sequencing of an ESBL-producing

Md Hafizur Rahman; Md Zulfekar Ali; Kazi Injamamul Hoque; Mahmudul Hasan

doi:10.1128/mra.00839-25

September 12, 2025

Genome sequencing of an ESBL-producing

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Key Points

The genome sequence shows the presence of 11 antibiotic resistance genes and 2 biocide resistance genes, which raise concerns for treatment options.
Six plasmids harboring virulence genes were identified in the Escherichia coli strain, emphasizing its potential pathogenicity.
This analysis was conducted on a strain isolated from a live bird market, suggesting risks associated with animal-to-human transmission.
Findings highlight the importance of monitoring antibiotic resistance in pathogens from animal sources, which is crucial for public health.

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Implication

Genome sequence analysis reveals multiple antibiotic resistance genes in Escherichia coli from birds, indicating potential public health risks.

Abstract

We report the genome sequence of an ESBL-producing Escherichia coli BLRI_001 strain (O8:H11, ST6018, phylogroup A) isolated from a live bird market in Dhaka, Bangladesh, harboring blaTEM-176, blaEC-15, with 6 replicon plasmids, 13 virulence genes, 11 antibiotic resistance genes, and 2 biocide resistance genes.

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Rahman et al. (2025) studied this question.

synapsesocial.com/papers/68c6df6de03a6c7bdc170fa7 https://doi.org/10.1128/mra.00839-25

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Genome sequencing of an ESBL-producing

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Abstract

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Genome sequencing of an ESBL-producing

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