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September 14, 2025

Application of Allogeneic Hematopoietic Stem Cell Transplantation in Elderly Patients with Acute Myeloid Leukemia--Review.

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Authors

XBXin BiPYPei-Pei Ye

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Overview

Review highlights treatment strategies and improved outcomes in elderly patients with acute myeloid leukemia, suggesting an optimal approach with allo-HSCT.

Key Points

  • Elderly patients with acute myeloid leukemia experience poorer outcomes and increased risks of treatment-related toxicity.
  • With advancements in reduced-intensity conditioning, elder AML patients now have more treatment options available.
  • Allogeneic hematopoietic stem cell transplantation offers a promising approach to improve prognosis in elderly patients.
  • Comorbidities in elderly patients with AML complicate treatment and require careful management during therapy.

Cite This Study

Bi et al. (2025) studied this question.

synapsesocial.com/papers/68c6df6de03a6c7bdc170fe3https://doi.org/10.19746/j.cnki.issn.1009-2137.2025.04.045
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Transplant Eligible and Ineligible Elderly Patients with AML—A Genomic Approach and Next Generation Questions2024 · 1 citations
  2. 2Allogeneic Hematopoietic Stem Cell Transplantation for Older Patients with Hematological Malignancies2025 · 1 citations
  3. 3Latest Insights and Progress in the Clinical Management of Elderly Patients with Acute Myeloid Leukemia: From Genetic Advancements to Targeted Treatments2024
  4. 4Improvements in Posttransplant Outcomes Over Two Decades in Older Patients with Acute Myeloid Leukemia in the EBMT ALWP Study2024 · 25 citations
  5. 5Cellular therapies in older adults with hematological malignancies: A case-based, state-of-the-art review2024 · 13 citations