September 16, 2025

Phytochemical profiling and bioactivity validation of Moringa oleifera leaves: Antimicrobial, antidiarrheal, analgesic, and in silico insights.

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Observational analysis found broad-spectrum antimicrobial effects in Moringa oleifera leaves, indicating potential for alternative therapies.

Moringa oleifera leaves showed significant antimicrobial activity, inhibiting Pseudomonas aeruginosa and Salmonella typhi by 19 mm.
Against diarrhea, a 400 mg/kg dose reduced episodes by 58.06%, while the analgesic assay showed a 59.18% decrease in writhing.
Using GC-MS/MS, 79 bioactive compounds were identified, with strong binding seen in molecular docking to therapeutic targets.
Highlights the potential for Moringa oleifera as an adjunct therapy, though less potent than established synthetic drugs.

Taher et al. (2025) studied this question.

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Observational analysis found broad-spectrum antimicrobial effects in Moringa oleifera leaves, indicating potential for alternative therapies.