Etablierung und Optimierung einer routinemäßigen Resistenzbestimmung von Helicobacter pylori zur Förderung einer resistenzgerechten Eradikationstherapie

The treatment of Helicobacter pylori infection, so far, focussed on empirical antibiotic regimens. Facing increasing resistance dynamics and regionally different resistance patterns, however, resistance testing respectively resistance-guided therapy appears to be more appropriate. This helds not only in order to increase the effectiveness of individual therapy, but also in the sense of antibiotic stewardship. In particular, in the context of predominantly gastroscopic diagnostics, various options for resistance testing using culture and PCR are available. Thus, the optimal resistance-oriented therapy regimens can be derived on an individual basis.