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September 12, 2025International Journal of NanomedicineOpen Access

Peri-Lymph Node Tattooing with Carbon Nanoparticles Suspension: A Novel Strategy for Targeted Axillary Dissection in Breast Cancer

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Authors

JLJiayang LiNZNengying ZhangZYZhongliang Yan

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Overview

This observational analysis evaluates targeted axillary dissection post-neoadjuvant therapy, suggesting improved diagnostic accuracy with carbon nanoparticles.

Key Points

  • The method showed 88.9% sensitivity and 100% specificity for detecting lymph nodes in breast cancer.
  • In the cN(+) group, 10 out of 18 patients had negative targeted lymph nodes after treatment.
  • Quantification of CNS-stained area indicated significant distribution differences in lymph nodes and surrounding tissues.
  • Peri-lymph node tattooing proved to be a feasible and effective strategy, reducing surgical morbidity.

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/68d44a4031b076d99fa538f7https://doi.org/10.2147/ijn.s541016
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Feasibility and accuracy of targeted axillary dissection by carbon tattooing in biopsy‐proven node‐positive breast cancer: A prospective study2025
  2. 2Carbon (charcoal) tattoo localization of biopsy-proven metastatic axillary lymph nodes for targeted axillary dissection after neoadjuvant therapy in breast cancer: a systematic review and single -arm meta-analysis2026 · 1 citations
  3. 3Abstract PS2-05-04: Single-dye sentinel lymph node mapping for targeted axillary dissection in breast cancer patients after neoadjuvant chemotherapy: a prospective study2026
  4. 4Wire-Free Targeted Axillary Dissection: A Pooled Analysis of 1300+ Cases Post-Neoadjuvant Systemic Therapy in Node-Positive Early Breast Cancer2024 · 8 citations
  5. 5Melanin-Based Nanoparticles for Lymph Node Tattooing: Experimental, Histopathological and Ultrastructural Study2024 · 4 citations