Cross-sectional study reveals acute improvements in anxiety symptoms through cranial electrotherapy stimulation, suggesting its potential as a treatment option.
Introduction: Patients with anxiety disorders are encountered commonly in clinical practice. Certain studies have highlighted the effectiveness of cranial electrotherapy stimulation (CES) in addressing both key aspects of anxiety symptoms. This study seeks to evaluate the immediate effectiveness of CES in managing anxiety symptoms. Materials and Methods: The study involved patients having anxiety and were administered one CES session for 20 min. The efficacy was evaluated by measuring physiological markers of anxiety along with subjective ratings pre and post the session. Results: 100 participants (61 females and 39 males), aged 18–80 years, were included with majority diagnosed with major depressive disorder accompanied by anxious distress. Statistically significant improvement in physiological markers of anxiety as well as subjective improvement in anxiety levels with just one session of CES was reported. Conclusions: CES is safe treatment option for anxiety disorders, and larger sample size studies to establish its efficacy are warranted.
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Rathod et al. (2025) studied this question.
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