Case report reveals manic symptoms in a hypothyroid patient, suggesting a link between hypothyroidism and mood disorders.
Thyroid dysfunction and psychiatric disorders are well connected to each other. A major contribution to this is hypothyroidism, most commonly presented as depressive symptoms. Mania in a patient with hypothyroidism is rarely to be seen. However, we encountered a case of 26-year-old single female, who has been a known case of hypothyroidism for the last 10 years, and presented with manic symptoms while being in a hypothyroid state herself. As per Diagnostic and Statistical manual of Mental disorder 5th edition, she was diagnosed as ‘Bipolar 1 disorder, Moderate, current or most recent episode manic (296.42) (F31.12)’. We treated her with mood stabilizer, antipsychotic, and dose adjustment in thyroid supplement drugs. It is thus to be emphasized that all patients of psychiatric diseases, especially mood disorders are to be screened for hypothyroidism, which would aid in a better understanding of the link between the two and ultimately to the prognosis of the disease.
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Sachi et al. (2025) studied this question.
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