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September 12, 2025BioChemOpen Access

Osteoporosis: Focus on Bone Remodeling and Disease Types

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This review highlights risk factors and mechanisms behind osteoporosis, emphasizing early diagnosis and treatment for effective fracture prevention.

Osteoporosis increases fracture risk and can significantly impact morbidity and mortality.
Bone remodeling imbalance occurs when osteoclast activity exceeds that of osteoblasts, contributing to osteoporosis.
Primary osteoporosis includes postmenopausal and age-related types, necessitating specialized treatment approaches.
Secondary osteoporosis may arise from conditions like hormonal imbalances or prolonged glucocorticoid use, indicating the need for comprehensive assessment.

Castellani et al. (2025) studied this question.

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This review highlights risk factors and mechanisms behind osteoporosis, emphasizing early diagnosis and treatment for effective fracture prevention.