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Endometrial Gastric-Type Adenocarcinoma Arising in the Background of Mucinous Metaplasia: A Case Report

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A 70-year-old woman diagnosed with unusual endometrial gastric-type adenocarcinoma, which is rare yet significant in cancer pathology.
Key immunohistochemical findings included positive CK20, CDX2, and MUC6 in the mucinous metaplasia, but MUC6 was absent in the adenocarcinoma.
The histologic features of this tumor complicate its diagnosis, underscoring the necessity of differential diagnosis in similar cases.
One year after surgery, the patient showed no signs of recurrence, suggesting a favorable initial outcome despite the tumor's rarity.

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A case report reveals endometrial gastric-type adenocarcinoma's link to mucinous metaplasia, emphasizing careful diagnosis.

Pongsada Prasonguppatum (2025) studied this question.

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