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September 12, 2025APL BioengineeringOpen Access

Analysis of immune cell infiltration landscape and identification of diagnostic biomarkers in ankylosing spondylitis

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Authors

MCM. L. ChenSZShanbang ZhuYGYue Gu

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Overview

Analysis identifies immune cell-related biomarkers in ankylosing spondylitis, suggesting diagnostic potential.

Key Points

  • Three genes associated with immune cells were identified as potential biomarkers for diagnosing ankylosing spondylitis.
  • The study confirmed the differential expression of CX3CR1, which was down-regulated in patients with ankylosing spondylitis.
  • Weighted gene co-expression network analysis identified seven candidate biomarkers related to immune cells in ankylosing spondylitis.
  • Dysregulation of macrophage ratios and biomarkers provides insights into the pathophysiology of ankylosing spondylitis.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68d44c3d31b076d99fa55854https://doi.org/10.1063/5.0252297
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