Systematic review identifies key predictors of lumbar degenerative spine diseases, suggesting targeted interventions may improve outcomes.
Lumbar degenerative spine diseases (LDSD) are a major source of chronic pain and disability around the globe, greatly affecting individuals' quality of life. The development of LDSD is shaped by a mix of genetic, environmental, and lifestyle factors, but the specific predictors are not well understood. This study seeks to identify and examine the main predictors of LDSD through an in-depth analysis of clinical, demographic, and behavioral factors. By assessing variables such as age, body mass index, physical activity levels, genetic predisposition, and occupational strain, this research aims to provide insights for the early detection and prevention of LDSD. The results are intended to guide targeted interventions and enhance patient outcomes by facilitating personalized treatment strategies.
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Ogunleye et al. (2025) studied this question.
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