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September 12, 2025Journal of the Grodno State Medical UniversityOpen Access

Clinical, Laboratory and Echocardiographic Left Atrial Appendage Thrombus Predictors in Patients With Atrial Fibrillation

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Authors

LKL. V. KalatseiAIAhmed S. IbrahimECEnrique F. Castillo

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Overview

This study reveals predictors of left atrial appendage thrombus in patients with atrial fibrillation, highlighting the role of NT-proBNP and duration of AF.

Key Points

  • Patients with left atrial appendage thrombus had a longer duration of persistent atrial fibrillation.
  • The NT-proBNP level of ≥ 1689 pg/ml showed the largest ROC area (0.747), indicating strong predictive ability.
  • Echocardiography revealed a higher left atrial volume index in patients with thrombus compared to those without.
  • GFR was significantly different between groups, with a p-value of 0.047 suggesting clinical relevance.

Cite This Study

Kalatsei et al. (2025) studied this question.

synapsesocial.com/papers/68d44c3d31b076d99fa55908https://doi.org/10.25298/2221-8785-2025-23-4-331-336
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Fibrosis biomarkers as predictors of left atrial appendage thrombosis in patients with nonvalvular atrial fibrillation2022 · 2 citations
  2. 2Noninvasive Surrogate Markers to Predict Thrombogenesis in Patients with Nonvalvular Atrial Fibrillation2016
  3. 3Left Ventricular Ejection Fraction Is Associated with the Risk of Thrombus in the Left Atrial Appendage in Patients with Atrial Fibrillation2020 · 25 citations
  4. 4Biomarkers for Predicting Left Atrial or Left Atrial Appendage Thrombus in Anticoagulated Patients with Nonvalvular Atrial Fibrillation2020 · 14 citations
  5. 5Mean Platelet Volume as a Predictor of Left Atrial Appendage Thrombus Resistance to Lysis in Patients With Atrial Fibrillation: Results of a 12-Month Follow-Up2025