Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 12, 2025MoleculesOpen Access

A Simple and Reliable Method for the Determination of Isorhapontigenin in Murine Biological Matrices: Application in a Tissue Distribution Study

View Full Paper
Ask AI
Bookmark
Share

Authors

YYYuhui YangHJHyou-Ju JinBLBoyu Liao

Discussion

Loading...

Member takes

Overview

This method quantifies isorhapontigenin in murine tissues, demonstrating its potential as a nutraceutical.

Key Points

  • The validated HPLC method allows accurate quantification of isorhapontigenin in murine biological matrices.
  • With a lower limit of quantification of 15 ng/mL, the method exhibits excellent selectivity and precision.
  • Following oral administration at a dose of 200 µmol/kg, isorhapontigenin shows rapid absorption and wide distribution in key organs.
  • These findings suggest isorhapontigenin has significant bioavailability and a favorable profile for nutraceutical applications.

Cite This Study

Yang et al. (2025) studied this question.

synapsesocial.com/papers/68d44c4631b076d99fa55a7ahttps://doi.org/10.3390/molecules30173635
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1An RP-HPLC method development and validation of organic impurities in isotretinoin2024 · 1 citations
  2. 2Isorhamnetin: what is the in vitro evidence for its antitumor potential and beyond?2024 · 22 citations
  3. 3A Validated UPLC–MS/MS Assay for Isosakuranetin Determination in Rat Plasma and Its Application to Pharmacokinetics2026
  4. 4Simultaneous identification and detection of four novel isoxazoline drugs in bovine-origin foods using ultra-high performance liquid chromatography coupled to quadrupole/linear ion trap mass spectrometry2025 · 1 citations
  5. 5Determination of Gnetol in Murine Biological Matrices by Liquid Chromatography–Tandem Mass Spectrometry (LC–MS/MS): Application in a Biodistribution Study2025 · 1 citations