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Analysis identifies miR-15a and Morgana as potential biomarkers in chronic myeloid leukemia, suggesting improved diagnostic strategies.
Chronic myeloid leukemia (CML) is a type of leukemia characterized by myeloid proliferation. Morgana is a chaperone protein, whose levels are lower due to the overexpression of miR-15a in CP phase. By quantitatively detecting miR-15a and Morgana, we could verify the correlation of them to CP-CML, thus as biomarkers of CP-CML diagnosis.
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Huang et al. (2025) studied this question.
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