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September 12, 2025Journal of Basic & Clinical Medical SciencesOpen Access

Nutritional status and postoperative outcomes in patients undergoing major resection for gastrointestinal cancer: a prospective cohort study

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Authors

MKMuhammad Attaullah KhanLady Reading HospitalMDMuhammad DaudIHIhtisham Ul HaqUniversity of Science and Technology of China

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Overview

This prospective cohort study finds that malnutrition increases postoperative complications in gastrointestinal cancer patients, indicating a need for better nutritional assessment.

Key Points

  • Malnourished patients had a significantly higher 30-day mortality rate of 12.5%, highlighting the risks of poor nutritional status.
  • The incidence of major complications was 35.9% in malnourished patients compared to 18.1% in well-nourished individuals, suggesting stronger perioperative care is needed.
  • Analysis revealed severe malnutrition as an independent risk factor, with an odds ratio of 2.84, emphasizing its impact on surgical outcomes.
  • Routine nutritional screening and tailored interventions could mitigate adverse postoperative outcomes for patients undergoing GI cancer surgery.

Cite This Study

Khan et al. (2025) studied this question.

synapsesocial.com/papers/68d44c5531b076d99fa560fdhttps://doi.org/10.58398/0002.000022
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Malnourished, gastrointestinal cancer patients undergoing surgery: burden of nutritional risk, use of oral nutritional supplements, and impact on health outcomes.2025 · 1 citations
  2. 2FP2.2 - Does preoperative nutritional assessment correlate with postoperative outcomes of patients undergoing surgery due to colorectal cancer? A bicenter prospective observational study2024
  3. 3Retrospective analysis of preoperative nutritional status and postoperative complications in gastric cancer surgery2025
  4. 4The Impact of Malnutrition Risk and Perioperative Complications in Gastrointestinal Cancer Patients Undergoing Elective Major Surgery: A Prospective Observational Multicenter Study2026
  5. 5Influence and assessment of nutritional status in patients undergoing treatment for colorectal cancer2026