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September 12, 2025AJP Regulatory Integrative and Comparative PhysiologyOpen Access

Hypoxia-induced impairments in fasting glucose are associated with acute mountain sickness severity during four days of residence at 4,300 m

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Authors

SLSean P. LanganUniversity of Connecticut ETEmily C. TagesenU.S. Army Research Institute of Environmental Medicine SLSteven D. LandspurgU.S. Army Research Institute of Environmental Medicine

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Implication

Observational analysis reveals impaired glucose metabolism correlates with acute mountain sickness severity, highlighting roles of hypoxia and insulin resistance.

Key Points

Impaired glucose metabolism during high altitude exposure is linked to acute mountain sickness severity.
Insulin resistance and transient glucose fluctuations were observed across four days at high altitude (4,300 m).
Active ascender Soldiers exhibited higher energy expenditure and lower oxygen saturation during ascent.
Higher levels of norepinephrine and glucose were significantly correlated with acute mountain sickness symptoms.

Cite This Study

Langan et al. (2025) studied this question.

synapsesocial.com/papers/68d44c5531b076d99fa56129 https://doi.org/10.1152/ajpregu.00130.2025

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Implication

Observational analysis reveals impaired glucose metabolism correlates with acute mountain sickness severity, highlighting roles of hypoxia and insulin resistance.

Hypoxia-induced impairments in fasting glucose are associated with acute mountain sickness severity during four days of residence at 4,300 m

Discussion

Member takes

Implication

Key Points

Cite This Study

Hypoxia-induced impairments in fasting glucose are associated with acute mountain sickness severity during four days of residence at 4,300 m

Discussion

Member takes

Implication

Key Points

Cite This Study

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