Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 12, 2025Open Access

Simple theoretical models predict some - but not all - aspects of the experimental evolution of antibiotic resistance

View Full Paper
Ask AI
Bookmark
Share

Authors

ELElin LiljaRARosalind J. AllenBWBartłomiej Waclaw

Discussion

Loading...

Member takes

Overview

Verification of a mathematical model for predicting antibiotic resistance evolution, highlighting modification needs.

Key Points

  • The model fails to reproduce key aspects of resistance evolution, particularly varying by antibiotic type.
  • Modifications to the model enhance its predictive power for bacterial resistance evolution outcomes.
  • Experimental setups in bioreactors validate assumptions of the mathematical model, noting discrepancies.
  • Quantitative modelling is crucial for understanding and managing antibiotic resistance dynamics.

Cite This Study

Lilja et al. (2025) studied this question.

synapsesocial.com/papers/68d44c5531b076d99fa561c4https://doi.org/10.1101/2025.09.07.674561
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Simple birth-death-mutation models predict some—but not all—aspects of the experimental evolution of antibiotic resistance2026
  2. 2Mathematical modelling of antibiotic interaction on evolution of antibiotic resistance: an analytical approach2024 · 1 citations
  3. 3Mapping the landscape of mathematical models for antimicrobial resistance: a scoping review2026
  4. 4Forecasting multi-trait resistance evolution under antibiotic stress2026
  5. 5From cells to populations: multi-scale quantitative approaches to antimicrobial resistance2026