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September 14, 2025Bioresources and BioprocessingOpen Access

Sustainable β-carotene production by engineered S. cerevisiae using sucrose and agricultural by-products

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Authors

SBSuriyaporn BubphasawanKSKitisak SansatchanonPPPeerada Promdonkoy

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Overview

This research demonstrates sustainable β-carotene synthesis in Saccharomyces cerevisiae using sucrose and agricultural by-products, suggesting a cost-effective strategy.

Key Points

  • Production levels of β-carotene reached 23.30 mg/L, showing significant potential for economic sustainability.
  • By deleting the GAL80 gene, we optimized yeast for sucrose use, facilitating higher β-carotene synthesis without costly induction.
  • Utilizing agricultural by-products reduced medium costs by 73%, demonstrating economic viability in industrial settings.
  • Overall sustainability improvements highlight the advantages of using unrefined substrates in microbial production systems.

Cite This Study

Bubphasawan et al. (2025) studied this question.

synapsesocial.com/papers/68d44f7b31b076d99fa56cbfhttps://doi.org/10.1186/s40643-025-00936-y
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