What type of study is this?

This is a Systematic Review study.

September 16, 2025Psychotherapy and PsychosomaticsOpen Access

Integrative Systematic Review on Pharmacological, Psychotherapeutic and Neurostimulatory Treatment Options in Treatment-Resistant Anxiety Disorders

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Authors

MSMiriam A. SchieleUniversity of Freiburg HFHarry FaganIsle of Wight NHS Trust DBDavid S. BaldwinSupélec

Discussion

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Implication

Integrative review explores pharmacological and psychotherapeutic approaches, suggesting effective therapies for treatment-resistant anxiety disorders.

Key Points

Treatment-resistant anxiety disorders pose significant challenges, impacting quality of life and public health.
Randomised controlled trials show SSRIs and clomipramine are effective after CBT failure in panic disorder.
Assessment of 26 RCTs and 36 open-label studies reveals mixed results and highlights the need for better methodologies.
Innovative treatments like ketamine and mindfulness-based therapy show promise, yet more research is needed for definitive recommendations.

Cite This Study

Schiele et al. (2025) studied this question.

synapsesocial.com/papers/68d44f8331b076d99fa5701c https://doi.org/10.1159/000547926

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Implication

Integrative review explores pharmacological and psychotherapeutic approaches, suggesting effective therapies for treatment-resistant anxiety disorders.

Integrative Systematic Review on Pharmacological, Psychotherapeutic and Neurostimulatory Treatment Options in Treatment-Resistant Anxiety Disorders

Discussion

Member takes

Implication

Key Points

Cite This Study

Integrative Systematic Review on Pharmacological, Psychotherapeutic and Neurostimulatory Treatment Options in Treatment-Resistant Anxiety Disorders

Discussion

Member takes

Implication

Key Points

Cite This Study

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