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September 16, 2025Autism Research

Developmental Shift From Intrinsic Hyper‐ to Hypo‐Connectivity Occurring at Pre‐Adolescence in Autism Spectrum Disorder

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Authors

XSXiaolong ShanTsinghua University LYLI YaShihezi University JXJinming XiaoUniversity of Electronic Science and Technology of China

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Implication

Observational analysis reveals a developmental shift to hypo-connectivity in key brain networks at pre-adolescence in autism spectrum disorder, highlighting age-related changes.

Key Points

A developmental shift from hyper- to hypo-connectivity occurs in autism spectrum disorder at pre-adolescence.
The study identified six large-scale brain functional networks, revealing differences in their connectivity patterns.
Independent component analyses were used to assess functional connectivity across 800 participants from a major autism dataset.
These findings highlight the need for a developmental perspective in understanding functional connectivity in autism spectrum disorder.

Cite This Study

Shan et al. (2025) studied this question.

synapsesocial.com/papers/68d44f8331b076d99fa5714c https://doi.org/10.1002/aur.70117

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Implication

Observational analysis reveals a developmental shift to hypo-connectivity in key brain networks at pre-adolescence in autism spectrum disorder, highlighting age-related changes.

Developmental Shift From Intrinsic Hyper‐ to Hypo‐Connectivity Occurring at Pre‐Adolescence in Autism Spectrum Disorder

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Implication

Key Points

Cite This Study

Developmental Shift From Intrinsic Hyper‐ to Hypo‐Connectivity Occurring at Pre‐Adolescence in Autism Spectrum Disorder

Discussion

Member takes

Implication

Key Points

Cite This Study

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