New method demonstrates tandem Giese/C-H functionalization of 3-indole-α-ketoacids, highlighting effective use of visible light.
An efficient method for forming cyclopenta[b]indoles directly from 3-indole-α-ketoacids via tandem Giese/C-H functionalization has been developed. The use of photoactive 3-indole-α-ketoacids as radical precursors allows for the mild tandem radical reaction to be enabled by visible light without the need for any metals, photocatalysts, or base.
No takes yet. Share an insight, caveat, or question.
Kitcatt et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: