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September 16, 2025European PsychiatryOpen Access

Limited Changes in Red Blood Cell Parameters after Probiotic Supplementation in Depressive Individuals: Insights from a Secondary Analysis of the Pro-Demet RCT

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Authors

OGOliwia Gawlik-KotelnickaMedical University of Lodz AGAgnieszka GajewskaFaculty (United Kingdom)AWAdam WysokińskiMedical University of Lodz

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Implication

Analysis shows limited changes in red blood cell parameters in depressed individuals after probiotic supplementation, suggesting further research is needed.

Key Points

Probiotic supplementation did not significantly change red blood cell parameters in participants with depression.
No significant statistical differences were noted in red blood cell metrics compared to the placebo group.
The analysis involved a two-arm, 60-day, RCT with 89 participants assessing various RBC-related markers.
Results indicate limited benefits of probiotics in modifying RBC parameters, underscoring the need for more detailed studies.

Cite This Study

Gawlik-Kotelnicka et al. (2025) studied this question.

synapsesocial.com/papers/68d4507931b076d99fa57d1d https://doi.org/10.1192/j.eurpsy.2025.1323

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Implication

Analysis shows limited changes in red blood cell parameters in depressed individuals after probiotic supplementation, suggesting further research is needed.

Limited Changes in Red Blood Cell Parameters after Probiotic Supplementation in Depressive Individuals: Insights from a Secondary Analysis of the Pro-Demet RCT

Discussion

Member takes

Implication

Key Points

Cite This Study

Limited Changes in Red Blood Cell Parameters after Probiotic Supplementation in Depressive Individuals: Insights from a Secondary Analysis of the Pro-Demet RCT

Discussion

Member takes

Implication

Key Points

Cite This Study

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