Case report describes a rare mesenchymal tumor causing significant dyspnea in a 47-year-old woman, highlighting surgical resection challenges.
A giant solitary fibrous tumor is a rare mesenchymal tumor of fibroblastic differentiation that is mainly located intrathoracically. It is not associated with specific risk factors. It has nonspecific clinical features and slow growth. The diagnosis is usually incidental and in large-size cases, representing a major surgical challenge. We present a case of a 47-year-old woman with no toxic habits, with no pathological history, who presented four days before admission with worsening dyspnea that had been progressively developing over the past five years, reaching Sadoul stage V without cough, sputum, hemoptysis, or chest pain. All of this occurred in the context of apyrexia and deterioration of her general condition. Her chest X-ray showed a near-complete opacification of the left hemithorax, with displacement of the mediastinum towards the right. This study was supplemented by a computed tomography (CT), which demonstrated a well-circumscribed, non-homogenous mass, occupying the entirety of the left hemithorax. An ultrasound-guided biopsy with pathological examination revealed a fusiform tumor proliferation of mesenchymal appearance. Complete surgical resection of the tumor is the only treatment with curative potential.
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Oulahbib et al. (2025) studied this question.
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