Supplementary Figure S2 from Phase Ib Study of Pembrolizumab in Combination with Intratumoral Injection of Clostridium novyi-NT in Patients with Advanced Solid Tumors

Key Points

Lymphocyte infiltration in tumor biopsies is observed, indicating immune response activation.
Patients with advanced solid tumors received pembrolizumab alongside clostridium novyi-NT injections in this study.
The findings highlight the potential of combining immunotherapy with intratumoral injections for advanced cancers.
These results call for further investigation into immunotherapy combinations in cancer treatments.

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Phase Ib study shows lymphocyte infiltration in tumor biopsies from patients with advanced solid tumors, suggesting immunotherapy potential.

Supplementary Figure S2. Lymphocyte infiltration in tumor biopsies.

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Nelson et al. (2025) studied this question.

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