Primary Infratentorial Central Nervous System Neuroblastoma: Case Report and Review from Paediatric Population

Background: Neuroblastomas of the central nervous system are rare malignant neoplasms that predominantly affect children. The neoplasia can present a wide variety of symptoms depending on its location and size. It has been documented predominantly in the supratentorial and spinal regions. The objective is to report an infratentorial pedriatric neuroblastoma case and review of the literature. Methods: The case of a patient diagnosed with neuroblastoma was reported. In addition, an exhaustive review of the literature between the years 1966 to 2024 was carried out. Results: From our cohort study, we found 197 patients, including our patient. Of the total number of cases, 195 were supratentorial; 49 frontal, 14 fronto-parietal, 7 fronto-temporal, 2 fronto-temporo-parietal, 9 temporal, 6 temporo-parietal, 3 temporo-parieto-occipital, 23 parietal, 13 parieto-occipital, and 6 occipital cases. Conclusion: Neuroblastoma is a high-grade neoplasm (WHO grade 4) with predominantly supratentorial involvement. We present a pediatric case of infratentorial neuroblastoma and a review of the literature.