Effectiveness of a Mobile Telerehabilitation Tool Versus Conventional Treatment in Total Knee Replacement: A Randomized Open-Label Controlled Trial

Abstract Purpose: To assess the effectiveness and safety of mobile tools guided by artificial intelligence versus conventional rehabilitation during the first 3 postoperative months following total knee replacement (TKR). Methods: An open-label, randomized controlled clinical trial was conducted in patients undergoing TKR, comparing interactive virtual telerehabilitation (IVT) with a control group receiving home-based physical therapy. Primary outcomes included adherence, pain measured by the visual analogue pain scale, knee range of motion, Oxford knee scale for functionality, and satisfaction at the end of follow-up. Results: A total of 210 patients were included (102 in the conventional group and 108 in TVI group), with a mean age of 68.14 years (standard deviation: 7.98 years); the majority of the participants were women (63.81%). Both groups showed similar results in pain control and range of mobility; however, functionality and adherence were significantly higher in the IVT group (p < 0.05). Only one adverse event was reported in the IVT group (a minor fall), which did not require hospital care. Conclusions: IVT was associated with higher adherence and greater functional improvement compared to conventional physical therapy. Level of evidence I