Observational analysis of cancer screening rates shows significant gaps in lung cancer detection, implying MCD tests are not yet viable.
The primary goal of cancer screening is to reduce cancer mortality. The U.S. Preventive Services Task Force (USPSTF) recommends average-risk screening for 4 cancer types: colorectum, cervix, breast, and lung (with a sufficient smoking history). About 70% of eligible women are up to date for cervix and breast, but less than 10% of eligible adults are screened for lung cancer (1). Unfortunately, 70% of cancer deaths are due to malignancies for which there is no screening test. Multicancer detection (MCD) tests have generated popular enthusiasm to fill this screening void (2). Mostly blood-based, MCD tests measure various biologic …
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David S. Weinberg (2025) studied this question.
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