What type of study is this?

This is a Quantitative Study study.

September 16, 2025Statistics in MedicineOpen Access

Impact of Endpoint Delay on the Efficiency of Multi Arm Multi Stage Trials

View Full Paper

Ask AI

Bookmark

Authors

Analysis quantifies efficiency loss from endpoint delay in multi-arm multi-stage trials, suggesting timing is crucial.

More than 50% of expected efficiency gain is often lost due to delays exceeding one-third of recruitment time.
The study employs analytical methods to estimate pipeline patients' impact on expected sample size in trials.
Earlier interim analyses may harm MAMS designs with outcome delays by increasing inefficiency.
Conducting trials with outcome delays less than one-third of total recruitment length maximizes efficiency benefits.

Mukherjee et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark