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September 16, 2025Open Access

Postoperative Blood Pressure Does Not Affect Lactate Clearance in Cardiac Surgery: A Retrospective Observational Cohort Study

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Authors

JHJames HallUniversity of BirminghamGBGeorge BotrosIsland HospitalMKMichael KhilkinIsland Hospital

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Implication

Retrospective cohort study analyzes the link between blood pressure and lactate clearance post-cardiac surgery, suggesting blood pressure may not significantly affect outcomes.

Key Points

  • Lactate clearance occurs largely independently of postoperative blood pressures in the first 16 hours.
  • Average cleared lactate fraction at 16 hours post-surgery was 85.9%, indicating effective clearance.
  • Lower early systolic blood pressures showed a slight trend toward delayed lactate clearance, with p=0.14.
  • Inotropic support on postoperative day 1 was statistically significant for lactate clearance, p=0.03.

Cite This Study

Hall et al. (2025) studied this question.

synapsesocial.com/papers/68d4539c31b076d99fa5978chttps://doi.org/10.20944/preprints202509.1297.v1
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