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September 16, 2025NutrientsOpen Access

Exercise-Induced Changes in Enterohepatic Communication Are Linked to Liver Steatosis Resolution

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Exercise effectively reversed liver steatosis and improved glucose tolerance in mice on a high-fat diet.
Mice undergoing aerobic exercise showed significant shifts in gut microbiota and hepatic bile acid profiles.
Exercise influenced levels of specific bile acids, enhancing lipid metabolism and reducing hepatic damage.
These findings highlight the importance of gut microbiota in mediating exercise benefits for liver health.

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Long-term aerobic exercise improves liver steatosis in mice on a high-fat diet, suggesting changes in gut microbiota and bile acids play key roles.

Zou et al. (2025) studied this question.

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Long-term aerobic exercise improves liver steatosis in mice on a high-fat diet, suggesting changes in gut microbiota and bile acids play key roles.