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September 16, 2025Journal of Ophthalmic and Vision ResearchOpen Access

Deep Anterior Lamellar Keratoplasty Versus Penetrating Keratoplasty in Keratoconus: A Retrospective Study Using Coarsened Exact Matching

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Authors

FKFarid KarimianKHKiana HassanpourFSFarbod Semnani

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Overview

Retrospective study shows DALK superior in graft rejection rates and comparable in visual acuity in keratoconus.

Key Points

  • DALK significantly improved graft rejection-free survival compared to PKP in keratoconus patients.
  • Survival analysis revealed 95.3% graft survival at three years for DALK vs. 74.5% for PKP.
  • Corneal vascularization emerged as the primary risk factor for graft rejection across both procedures.
  • Both techniques yielded similar best-corrected visual acuity and suture complications.

Cite This Study

Karimian et al. (2025) studied this question.

synapsesocial.com/papers/68d454d831b076d99fa5aa8fhttps://doi.org/10.18502/jovr.v20.15222
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Deep anterior lamellar keratoplasty and penetrating keratoplasty in macular corneal dystrophy: comparison of visual and topographic outcomes and complications2024 · 5 citations
  2. 2Deep anterior lamellar vs penetrating keratoplasty for macular and granular stromal dystrophies: clinical and refractive results2026
  3. 3Deep anterior lamellar keratoplasty in advanced keratoconus in children: A 4-year study2024 · 1 citations
  4. 4Recurrence Rates and Predictive Risk Factors of Keratoconus After Penetrating and Deep Anterior Lamellar Keratoplasty2026
  5. 5Long-Term Graft Survival and Visual Outcomes in Deep Anterior Lamellar Keratoplasty (DALK): A Narrative Review.2026