Case report shows successful closure of recurrent full thickness macular hole with intravitreal injection and topical therapy, suggesting non-surgical alternatives.
A 73-year-old male with a past medical history of pseudophakia and posterior vitreous detachment (PVD) in both eyes, epiretinal membrane (ERM) in his right eye (OD), lattice degeneration OD, and prior, localized retinal detachment OD status post laser retinopexy presented with progressive vision loss OD. The patient was found to have a full thickness macular hole (FTMH) which was successfully closed with pars plana vitrectomy (PPV), the standard of treatment for a primary FTMH. Six years postoperatively, the macular hole reopened. The recurrent FTMH was managed with intravitreal injection of triamcinolone acetonide (Kenalog) 2.0 mg/0.05 mL and topical dorzolamide-timolol 2%/0.5%, ketorolac 0.4%, and prednisolone acetate 1% drops. This conservative management resulted in complete resolution of the recurrent FTMH. This case illustrates the efficacy of topical therapy in managing recurrent FTMH, highlighting a non-surgical alternative in select patients.
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Vroman et al. (2025) studied this question.
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