Longitudinal analysis reveals early-life and lifestyle factors significantly increase MASLD risk in children from China and the U.S.
Key Points
The risk score for MASLD indicates a 263% higher risk with each unit increase at follow-up, highlighting the impact of cumulative risk factors.
Exposure to second-hand smoke and sedentary behavior showed significant associations with MASLD in children, with odds ratios of 2.36 and 3.21, respectively.
Analysis of data from a survey in Beijing and the NHANES cohort used logistic regression methods to examine risk factors for MASLD.
These findings suggest essential targeted interventions to manage pediatric MASLD, especially considering the differences in populations.