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September 16, 2025Computers in Biology and MedicineOpen Access

Segmentation and quantification of atherosclerotic plaques in optical coherence tomography

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Authors

ВДВячеслав ДаниловVLVladislav V. LaptevKKK. Yu. Klyshnikov

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Overview

This analysis demonstrates machine learning enhances segmentation accuracy of plaque features in OCT, indicating better cardiovascular risk assessment.

Key Points

  • Automated segmentation achieved high accuracy for lumen (DSC: 0.987) in a diverse cohort of 103 patients.
  • The study utilized advanced machine learning models, including U-Net and DeepLabV3, optimizing accuracy for complex plaque structures.
  • A hybrid segmentation strategy employed single-class models for common features and multi-class models for complex morphologies.
  • Integration of models into a weighted ensemble significantly improved overall segmentation accuracy to a DSC of 0.882.

Cite This Study

Данилов et al. (2025) studied this question.

synapsesocial.com/papers/68d4566c31b076d99fa5b969https://doi.org/10.1016/j.compbiomed.2025.111061
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