Development of standardized eye atlases for spatial normalization in ophthalmic imaging, suggesting improved diagnostic capabilities.
Motivation: Lack of standardized tools for spatial normalization in eye MRI Goal(s): Develop unbiased eye atlases in MRI Approach: Through image registration, we create eye reference templates detailing healthy eye structures using T1w MR images Results: Publicly available large-scale unbiased T1w MR-Eye atlases for males (N=594), females (N=616), and combined (N=1210), along with their detailed labels for healthy eye and orbit structures, also projected onto MNI152 and Colin27 spaces Impact: The publicly provided large-scale unbiased T1w MR-Eye atlases will facilitate spatial normalization and quantitative analysis in the field of ophthalmic imaging, helping clinicians in the diagnosis of multiple ocular diseases, and enhancing our understanding in sex-specific eye anatomy and physiology.
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Barranco et al. (2025) studied this question.
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