Observational analysis reveals significant ECV value differences in rectal cancer stages, highlighting its diagnostic relevance.
Motivation: The ECV values measured by imaging examination are consistent with the amount of extracellular matrix measured by tissue biopsy. Goal(s): To investigate the preliminary application value of extracellular volume fraction in rectal cancer. Approach: A senior radiologist marked the layer of the maximum tumor on T1 mapping native and T1 mapping enhanced images. Results: The differences of ECV values of positive neuro aggression and negative group ,pT1-2 and pT3-4 tumors were statistically significant.The differences of ECV values of thrombus positive and negative group ,lymph node positive and negative group were statistically significant. Impact: Extracellular volume fraction has application value in rectal cancer.
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Zhang et al. (2025) studied this question.
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