Motivation: Multiparametric MRI on 5T has emerged as a pivotal diagnostic modality for evaluating body lesions, but its application in prostate imaging has not been fully explored. Goal (s): To evaluate the diagnostic efficacy of distinguishing PCa from BPH using multiparametric histogram analysis on 5. 0T MRI Approach: 85 patients underwent DWI, IVIM, and T2 mapping imaging on 5. 0T MRI, and diagnostic performance of combined ADCDD*fT2 model was assessed. Results: The combined ADCDD*fT2 model achieved an AUC of 0. 991 on 5T, significantly outperforming PSA testing in distinguishing PCa from BPH. Impact: This study demonstrates that 5. 0T MRI, with advanced histogram analysis, offers a reliable and non-invasive method for distinguishing prostate cancer from benign prostatic hyperplasia, enabling more accurate early diagnoses and reducing unnecessary biopsies in clinical settings.
Zheng et al. (Tue,) studied this question.