What type of study is this?

This is a Quantitative Study study.

September 17, 2025

Age Dependency of Diffusion-Relaxation Coupling in the Prostate

Key Points

Luminal water imaging parameters correlated weakly to moderately with age in healthy males, highlighting age's impact on imaging outcomes.
Utilizing time-efficient multi-readout diffusion-weighted imaging sequences enabled detailed exploration of age-dependent parameters.
The study suggests that advanced imaging techniques can enhance the evaluation of prostate lesions while considering age factors.
Findings indicate the potential for more accurate prostate diagnostics through improved imaging methodologies.

Abstract

Motivation: Luminal water imaging (LWI) strongly correlates with Gleason scores in the prostate, but conventional LWI imaging techniques are time consuming and may be confounded by age. Goal(s): Investigate the age dependency of luminal water fraction and other LWI parameters in the prostate. Approach: Use time-efficient multi-readout EPI sequences capable of acquiring images at multiple TEs in one shot to probe T2-ADC and T2*-ADC coupling in the prostate among healthy male subjects. Results: LWI parameters showed weak to moderate correlations with age. Impact: This study demonstrates the feasibility of using multi-readout DWI sequences to enable time-efficient investigation of age dependency of LWI parameters, providing valuable information for using LWI to evaluate prostate lesions.

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Cite This Study

Yen et al. (Tue,) studied this question.

synapsesocial.com/papers/68d4597031b076d99fa5c630 https://doi.org/https://doi.org/10.58530/2025/2291

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