The COMBINE method improves super-resolution MRI of rapidly decaying signals using non-Cartesian trajectories, suggesting wider clinical applications.
Motivation: MRI of tissues with fast signal decay at high resolution is challenging. The COMBINE method uses different signal combinations of RF phase-cycled bSSFP data to increase spatial resolution, though has only been applied to Cartesian trajectories. Goal(s): We aim to extend COMBINE to non-Cartesian trajectories, giving new opportunities for measuring rapidly decaying signals. Approach: We implement the COMBINE super-resolution approach with a 3D Cones SSFP acquisition, exploiting additional signal components extracted from RF phase-cycled SSFP datasets. Results: The proposed COMBINE 3D Cones acquisition gives the ability to resolve finer structures than the nominal acquisition trajectory. Impact: Non-Cartesian COMBINE opens new avenues for super-resolution UTE imaging and broadening clinical applications.
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Brnawi et al. (2025) studied this question.
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