3D High-Resolution Reduced Field-of-View T2-Weighted Imaging by Combining 3D EPI and Spatially Selective Pulses

Motivation: Multidimensional selective RF pulses combined with nonselective pulses has been studied in achieving reduced FOV (rFOV) imaging. However, combining of multiple spatial selective pulses may improve the spatial selectivity and help achieve 3D high-resolution rFOV imaging at 3T. Goal(s): To achieve high-resolution 3D rFOV T2-weighted images by using multidimensional RF pulses. Approach: Combining two 3D selective RF pulses respectively for excitation and refocusing, and a 3D EPI imaging sequence at a 3T scanner. Results: High-resolution 3D images of brain and prostate were acquired using proposed method. Impact: Our simulation and in vivo results demonstrated the potential of obtained high-resolution T2-weighted images in the brain and prostate. This shows the potential to achieve high-resolution diffusion imaging using rFOV imaging approach in the future study.