Pushing the Boundaries of Neuroimaging: A Practical Guide to 7T Single-Voxel MR Spectroscopy for Advanced Neurochemical Imaging

Motivation: By developing a reproducible protocol, we aim to support clinicians and researchers in capturing high- quality neurochemical data that could lead to earlier and more accurate diagnoses, tailored treatments, and a deeper understanding of the brain's metabolic landscape in health and disease. Goal(s): The goal is to develop a practical protocol for performing single-voxel MRS on the Siemens 7T Terra system and educating MR technologists to achieve high quality imaging. Approach: Patient positioning/Coil Selection, Parameter selection, Data acquisition/monitoring, Post-processing/analysis. Results: By using single-voxel approach, the Siemens 7T Terra system achieves more accurate detection of metabolic changes, crucial for research and diagnosis. Impact: A step-by-step guide will help clinicians, researchers and future MR Technologist with the process of scanning MR Spectroscopy on a 7T system. It will also serve as a guide to other technologists that have not had hands on training.