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This analysis demonstrates optimized 3D T1 VIBE Dixon sequences improve CSF leak detection, indicating enhanced clinical reliability.
Motivation: Regarding fat-suppressed 3D T1-wighted sequences employed for cerebrospinal fluid (CSF) leak detection, in the literature there is a paucity of details on the fat suppression technique employed and a lack of standardisation or discussion on the optimization of the technical aspects. Goal(s): Optimise 3D T1-wighted sequences that a) achieve complete fat suppression around the spinal canal and b) are feasible to implement on a wide range of scanners. Approach: Develop MR myelography sequences at 1.5T considering available sequence and fat suppression options. Results: Superior performance of Dixon fat suppression. Optimised VIBE-DIXON sequences detect leakage of contrast-opacified CSF in a clinical case. Impact: This study supports 3D spoiled gradient echo sequences with Dixon fat suppression as a reliable option for CSF leak assessment in clinical settings.
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Borri et al. (2025) studied this question.
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