Brain-wide functional mapping reveals deafening-induced cross-modal plasticity in mice

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BOLD-fMRI reveals that auditory deprivation significantly impacts sensory networks in mice, suggesting extensive cross-modal plasticity.

Deafening enhances responses to somatosensory and visual stimuli in mice, indicating brain adaptation.
Cross-modal plasticity emerged in the deprived auditory cortex, showing significant sensory network reorganization.
BOLD-fMRI and optical imaging confirmed sensory pathway changes following auditory input loss during the experiment.
These findings highlight that sensory deprivation can drive widespread brain reorganization even in adult animals.

Jung et al. (2025) studied this question.

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