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Evaluation of intravoxel incoherent motion (IVIM) to detect bone marrow ischemia and perfusion in a piglet model of Legg-Calvé-Perthes disease

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Evaluation of IVIM shows reduced perfusion in ischemic bone marrow, suggesting a viable non-contrast alternative for pediatric imaging.

IVIM effectively detected reduced perfusion in regions with ischemia compared to perfused areas.
The study used 3T MRI data from four piglets with varying levels of femoral head ischemia.
Gadolinium-enhanced MRI identified ischemic regions, serving as a comparative standard for IVIM analysis.
The findings indicate IVIM's potential to improve diagnosis in children with conditions like Legg-Calvé-Perthes disease.

Amann et al. (2025) studied this question.

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