Brain Artery Tortuosity Analysis Using 7 Tesla MRI Time of Flight Images

Motivation: The tortuosity of brain arteries may be a biomarker for age-related vascular changes. Understanding its variation with age and sex could have implications for vascular health assessment. Goal(s): This study aims to quantify brain artery tortuosity and analyze its correlation with age and variability by sex. Approach: Using high-resolution 7T MRI, brain arteries were segmented and analyzed to compute tortuosity metrics. Results: Tortuosity increased with age, showing greater variance in females, suggesting potential sex-specific differences in vascular health. Impact: This study establishes brain artery tortuosity as a promising biomarker for age-related vascular health. Sex-specific variance, underscores the potential for personalized vascular assessments, supporting tailored health interventions in aging populations.